20090420
The Achilles’ Heel of Aging § SEEDMAGAZINE.COM
The Achilles’ Heel of Aging § SEEDMAGAZINE.COM: "In humans sirtuin is coded for by a gene called SIRT1. Sirtuins have been conserved by natural selection for a very long time, more than a billion years, because they do something very important. When they’re switched on in an organism, they promote an ultra-protective “maintenance mode,” one that shields against the biochemical deterioration that increases the chance of disease over time. So it’s no accident that they play a role in controlling energy metabolism, endurance, and even the ability to resist cancer. And environmental stress, like calorie restriction, is what sends sirtuins into overdrive."